design and synthesis of new imidazole derivatives of captopril

نویسندگان

mh houshdar tehrani

afshin zarghi

l erfani jabarian

چکیده

a new series of alkylthio imidazole analogues of captopril, an ace inhibitor used in the treatment of hypertension, was designed and synthesized in order to obtain agents more active than captopril with less side effects. all the compounds thus prepared were purified and characterized by ir, nmr and mass analytical instruments.

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منابع مشابه

Design and Synthesis of New Imidazole Derivatives of Captopril

A new series of alkylthio imidazole analogues of captopril, an ACE inhibitor used in the treatment of hypertension, was designed and synthesized in order to obtain agents more active than captopril with less side effects. All the compounds thus prepared were purified and characterized by IR, NMR and Mass analytical instruments.

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Design and Synthesis of New Imidazole Derivatives of Captopril

A new series of alkylthio imidazole analogues of captopril, an ACE inhibitor used in the treatment of hypertension, was designed and synthesized in order to obtain agents more active than captopril with less side effects. All the compounds thus prepared were purified and characterized by IR, NMR and Mass analytical instruments.

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Novel Group of Imidazole Derivatives as Atypical Selective Cyclooxygenase-2 Inhibitors: Design, Synthesis and Biological Evaluation

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عنوان ژورنال:
iranian journal of pharmaceutical research

جلد ۲۰۰۵، شماره ۱، صفحات ۳۷-۴۱

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